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Article

Senescent endothelial cells are prone to TNF-α-induced cell death due to expression of FAS receptor.

Biochemical and biophysical research communications - 23 Aug 2013

Jeon Hyeona, Boo Yong Chool

Abstract excerpt

The senescent endothelial cells show various phenotypes which can increase the incidence of inflammatory cardiovascular diseases, but the fundamental basis for such phenotypic changes of senescing cells remains to be elucidated. This study was undertaken to find transmembrane receptors that might be highly expressed in senescent endothelial cells and play a key role in cell death signal transduction. Comparison...

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Source

Identifiers

PMID: 23880344
DOI: 10.1016/j.bbrc.2013.07.052

Genes

FAS
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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