Article
Heart grafts tolerized through third-party multipotent adult progenitor cells can be retransplanted to secondary hosts with no immunosuppression.
Stem cells translational medicine - 1 Aug 2013
Eggenhofer Elke, Popp Felix C, Mendicino Michael, Silber Paula, Van't Hof Wouter, Renner Philipp, Hoogduijn Martin J, Pinxteren Jef, van Rooijen Nico, Geissler Edward K, Deans Robert, Schlitt Hans J, Dahlke Marc H
Abstract excerpt
Multipotent adult progenitor cells (MAPCs) are an adherent stem cell population that belongs to the mesenchymal-type progenitor cell family. Although MAPCs are emerging as candidate agents for immunomodulation after solid organ transplantation, their value requires further validation in a clinically relevant cell therapy model using an organ donor- and organ recipient-independent, third-party cell product. We...
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