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HLA‐E high /HLA‐G high /HLA‐II low Human iPSC‐Derived Cardiomyocytes Exhibit Low Immunogenicity for Heart Regeneration

6 Sept 2023

Abstract excerpt

Abstract Although human pluripotent stem cells (hPSCs)‐derived cardiomyocytes (hPSC‐CMs) can remuscularize infarcted hearts and restore post‐infarct cardiac function, post‐transplant rejection resulting from human leukocyte antigen (HLA) mismatching is an enormous obstacle. It is crucial to identify hypoimmunogenic hPSCs for allogeneic cell therapy. This study is conducted to demonstrate the immune privilege of...

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PMID: 37672681
DOI: 10.1002/adhm.202301186

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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