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Immune reaction and regulation in transplantation based on pluripotent stem cell technology

30 Jun 2020

Abstract excerpt

The development of pluripotent stem cell (PSC)-based technologies provides us a new therapeutic approach that generates grafts for transplantation. In order to minimize the risk of immune reaction, the banking of induced pluripotent stem cells (iPSCs) from donors with homozygous human leukocyte antigen (HLA) haplotype is planned in Japan. Even though pre-stocked and safety validated HLA-homozygous iPSCs are...

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PMID: 32636970
DOI: 10.1186/s41232-020-00125-8

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