Article
Association of microRNA-196a-2 gene polymorphism with gastric cancer risk in a Chinese population.
Digestive diseases and sciences - 1 Aug 2010
Peng Sheng, Kuang Zhongshen, Sheng Chenyi, Zhang Yan, Xu Hang, Cheng Qinghong
Abstract excerpt
BACKGROUND: It has been proposed that single nucleotide polymorphisms (SNPs) in microRNAs (miRNAs) could affect the expression of the miRNA and contribute to the susceptibility of human tumors. However, the role of genetic variant (T/C) in miR-196a-2 in gastric cancer susceptibility is still unknown. OBJECTIVES: To evaluate the association between genetic polymorphism of miR-196a-2 (rs11614913) and risk of...
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