Article
Schizosaccharomyces pombe Sst4p, a conserved Vps27/Hrs homolog, functions downstream of phosphatidylinositol 3-kinase Pik3p to mediate proper spore formation.
Eukaryotic cell - 1 Dec 2007
Onishi Masayuki, Iida Michihiro, Koga Takako, Yamada Sadayuki, Hirata Aiko, Iwaki Tomoko, Takegawa Kaoru, Fukui Yasuhisa, Tachikawa Hiroyuki
Abstract excerpt
Sporulation of the fission yeast Schizosaccharomyces pombe is a developmental process that generates gametes and that includes the formation of spore envelope precursors called the forespore membranes. Assembly and development of forespore membranes require vesicular trafficking from other intracellular membrane compartments. We have shown that phosphatidylinositol 3-kinase (PtdIns 3-kinase) is required for...
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