Article
Role of phosphatidylinositol 3-phosphate in formation of forespore membrane in Schizosaccharomyces pombe.
Yeast (Chichester, England) - 1 Feb 2003
Onishi Masayuki, Koga Takako, Morita Rika, Nakamura Yoko, Nakamura Taro, Shimoda Chikashi, Takegawa Kaoru, Hirata Aiko, Fukui Yasuhisa
Abstract excerpt
Phosphatidylinositol (PI) 3-kinase (encoded by the pik3(+) gene) in Schizosaccharomyces pombe has been identified as a homologue of VPS34p, a protein required for proper vesicular protein sorting. The clone defective in this protein carries enlarged vacuoles and exhibits sensitivity to high temperature or high ion concentration. The effect of disruption of pik3(+) on sporulation of Sz. pombe was examined. The...
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