A genome-wide screen for sporulation-defective mutants in Schizosaccharomyces pombe.

doi:10.1534/g3.114.011049

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Article

A genome-wide screen for sporulation-defective mutants in Schizosaccharomyces pombe.

G3 (Bethesda, Md.) - 11 Apr 2014

Ucisik-Akkaya Esma, Leatherwood Janet K, Neiman Aaron M

Abstract excerpt

Yeast sporulation is a highly regulated developmental program by which diploid cells generate haploid gametes, termed spores. To better define the genetic pathways regulating sporulation, a systematic screen of the set of ~3300 nonessential Schizosaccharomyces pombe gene deletion mutants was performed to identify genes required for spore formation. A high-throughput genetic method was used to introduce each...

Topics

Gene Expression Regulation, Fungal
Genome-Wide Association Study
Haploidy
Meiosis
Mutation
Phenotype
Schizosaccharomyces
Schizosaccharomyces pombe Proteins
Sequence Deletion
Spores, Fungal

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Identifiers

PMID: 24727291
DOI: 10.1534/g3.114.011049
PMCID: PMC4065261

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