Article
Phosphatidylinositol 3-phosphate 5-kinase is required for the cellular response to nutritional starvation and mating pheromone signals in Schizosaccharomyces pombe.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Feb 2002
Morishita Masayo, Morimoto Fusako, Kitamura Kenji, Koga Takako, Fukui Yasuhisa, Maekawa Hiromi, Yamashita Ichiro, Shimoda Chikashi
Abstract excerpt
BACKGROUND: Phosphatidylinositol (3,5) bisphosphate, which is converted from phosphatidylinositol 3-phosphate by phosphatidylinositol 3-phosphate 5-kinase, is implicated in vacuolar functions and the sorting of cell surface proteins within endosomes in the endocytic pathway of budding yeast. A homologous protein, SpFab1p, has been found in the fission yeast Schizosaccharomyces pombe, but its role is not known....
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