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Article

Expression of VACM-1/cul5 mutant in endothelial cells induces MAPK phosphorylation and maspin degradation and converts cells to the angiogenic phenotype.

Microvascular research - 1 Mar 2008

Buchwalter A, Van Dort C, Schultz S, Smith R, Le I P, Abbott J L, Oosterhouse E, Johnson A E, Hansen-Smith F, Burnatowska-Hledin M

Abstract excerpt

Vasopressin-activated calcium mobilizing receptor (VACM-1) is a member of the cullin gene family involved in ubiquitin-proteosome dependent regulation of cellular functions. Expression of VACM-1 cDNA in cos-1 cells in vitro decreases basal cAMP levels and inhibits growth. The expression of (S730A...

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Identifiers

PMID: 17950367
DOI: 10.1016/j.mvr.2007.08.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17950367-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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