Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Truncated form of VACM-1/cul-5 with an extended 3' untranslated region stimulates cell growth via a MAPK-dependent pathway.

Biochemical and biophysical research communications - 19 May 2006

Sartor Ashleigh, Kossoris J B, Wilcox R, Shearer R, Zeneberg A E, Zhao P, Lazdins I, Burnatowska-Hledin Maria A

Abstract excerpt

We have sequenced a 4.9kb clone (KLB22) which shares 99% sequence homology with the rabbit vasopressin-activated calcium mobilizing (VACM-1) protein. The 5' terminus sequence of KLB22 cDNA (nucleotides 1-1961) is continuous and overlapping with nucleotides 1226-3186 of the VACM-1 cDNA sequence. The 3'UTR of KLB22 cDNA extends beyond the 3'UTR of VACM-1 by 2999nt. KLB22 cDNA encodes a 497 amino acid protein, which...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Cell Nucleus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chlorocebus aethiops

Share to COS Cells

Share to Cullin Proteins

Share to MAP Kinase Signaling System

Share to Rabbits

Share to Receptors, Vasopressin

Source

Identifiers

PMID: 16581022
DOI: 10.1016/j.bbrc.2006.02.197

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

Truncated form of VACM-1/cul-5 with an extended 3' untranslated region stimulates cell growth via a MAPK-dependent pathway.PMID 16581022Read ↗

VACM-1, a cul-5 gene, inhibits cellular growth by a mechanism that involves MAPK and p53 signaling pathways.Semantic proximity Read ↗

Expression of VACM-1/cul5 mutant in endothelial cells induces MAPK phosphorylation and maspin degradation and converts cells to the angiogenic phenotype.Semantic proximity Read ↗

Mutational analysis of VACM-1/cul5 exons in cancer cell lines.Semantic proximity Read ↗

Expression of a mutant myosin light chain that cannot be phosphorylated increases paracellular permeability.Semantic proximity Read ↗

Mutation analysis of the non-muscle myosin light chain kinase (MLCK) deletion constructs on CV1 fibroblast contractile activity and proliferation.Semantic proximity Read ↗

The p21 ras C-terminus is required for transformation and membrane association.Semantic proximity Read ↗

Molecular cloning and biochemical characterization of a truncated, secreted member of the human family of Ca2+-activated Cl− channelsSemantic proximity Read ↗

Molecular cloning and functional expression of a cDNA encoding the human V1b vasopressin receptor.Semantic proximity Read ↗

Epidermal growth factor-stimulated tyrosine phosphorylation of caveolin-1. Enhanced caveolin-1 tyrosine phosphorylation following aberrant epidermal growth factor receptor status.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.