Article
Identification of trf2 mutants of Drosophila with defects in anterior spiracle eversion.
Archives of insect biochemistry and physiology - 1 Apr 2007
Shima Seigo, Aigaki Toshiro, Nojima Tetsuya, Yamamoto Daisuke
Abstract excerpt
TATA-box-binding protein (TBP)-related factor (Trf)2 is a member of the family of TBP-related factors present in metazoan organisms. In Drosophila, Trf2 immunoprecipitates with the nucleosome remodeling factor (NURF) chromatin remodeling complex and the DNA replication element (DRE)-binding factor DREF. When it forms a complex with DREF, Trf2 activates transcription from the DRE-binding sites of the proliferating...
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