Article
The Putzig-NURF nucleosome remodeling complex is required for ecdysone receptor signaling and innate immunity in Drosophila melanogaster.
Genetics - 1 May 2011
Kugler Sabrina J, Gehring Eva-Maria, Wallkamm Veronika, Krüger Victoria, Nagel Anja C
Abstract excerpt
Putzig (Pzg) was originally identified as being an integral component of the TRF2/DREF complex in Drosophila melanogaster, thereby regulating the transcriptional activation of replication-related genes. In a DREF-independent manner, Pzg was shown to mediate Notch target gene activation. This function of Pzg entails an association with the nucleosome remodeling factor complex NURF, which directly binds the...
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