Article
The Drosophila homolog of NTF-2, the nuclear transport factor-2, is essential for immune response.
EMBO reports - 1 Apr 2002
Bhattacharya Ananya, Steward Ruth
Abstract excerpt
Nuclear transport factor-2 (NTF-2) functions in yeast and mammalian cell culture in targeting proteins into the nucleus. The Drosophila homolog, DNTF-2, is an essential component of the nuclear import machinery, since ntf mutants are lethal. Interestingly, hypomorphic alleles show specific phenotypes. Some are viable, but the number of omatidia in the eye is severely reduced. The immune response in the Drosophila...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
