Article
The PX-BAR membrane-remodeling unit of sorting nexin 9.
The EMBO journal - 14 Nov 2007
Pylypenko Olena, Lundmark Richard, Rasmuson Erika, Carlsson Sven R, Rak Alexey
Abstract excerpt
Sorting nexins (SNXs) form a family of proteins known to interact with components in the endosomal system and to regulate various steps of vesicle transport. Sorting nexin 9 (SNX9) is involved in the late stages of clathrin-mediated endocytosis in non-neuronal cells, where together with the GTPase dynamin, it participates in the formation and scission of the vesicle neck. We report here crystal structures of the...
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