Experimental Mouse Models of Asthma and Analysis of CD4 T Cells.

Abstract excerpt

Asthma is a highly prevalent lung disease, characterized by airway dysfunction and chronic inflammation. Asthma occurs in both children and adults, but frequently originates in early life. Heterogeneous asthma phenotypes exist, but Th2 cells are key players in a large proportion of cases, while other CD4+ T cell subsets are also implicated in driving and limiting pathology. In this chapter, we describe methods...

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• Mice, Inbred BALB C
• Research Design
• Workflow
• Asthma
• CD4-Positive T-Lymphocytes