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Article

Bcl11b mutations identified in murine lymphomas increase the proliferation rate of hematopoietic progenitor cells.

BMC cancer - 17 Oct 2007

Karlsson Anneli, Nordigården Amanda, Jönsson Jan-Ingvar, Söderkvist Peter

Abstract excerpt

BACKGROUND: The telomeric region of mouse chromosome 12 has previously shown frequent allelic loss in murine lymphoma. The Bcl11b gene has been identified and suggested as a candidate tumor suppressor gene within this region. In this study, we aimed to elucidate whether Bcl11b is mutated in lymphomas with allelic loss, and whether the mutations we detected conferred any effect on cell proliferation and apoptosis....

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Identifiers

PMID: 17941976
DOI: 10.1186/1471-2407-7-195
PMCID: PMC2140266

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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