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Article

Bcl11b—A Critical Neurodevelopmental Transcription Factor—Roles in Health and Disease

28 Mar 2017

Abstract excerpt

B cell leukemia 11b (Bcl11b) is a zinc finger protein transcription factor with a multiplicity of functions. It works as both a genetic suppressor and activator, acting directly, attaching to promoter regions, as well as indirectly, attaching to promoter-bound transcription factors. Bcl11b is a fundamental transcription factor in fetal development, with important roles for the differentiation and development of...

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PMID: 28424591
DOI: 10.3389/fncel.2017.00089

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