Article
Multisite and bidirectional exonic splicing enhancer in CD44 alternative exon v3.
RNA (New York, N.Y.) - 1 Dec 2007
Vela Elena, Hilari Josep M, Roca Xavier, Muñoz-Mármol Ana M, Ariza Aurelio, Isamat Marcos
Abstract excerpt
The human CD44 gene encodes multiple isoforms of a transmembrane protein that differ in their extracellular domains as a result of alternative splicing of its variable exons. Expression of CD44 is tightly regulated according to the type and physiological status of a cell, with expression of high molecular weight isoforms by inclusion of variable exons and low molecular weight isoforms containing few or no...
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