Article
Proteoglycan forms of the lymphocyte homing receptor CD44 are alternatively spliced variants containing the v3 exon.
The Journal of cell biology - 1 Feb 1995
Jackson D G, Bell J I, Dickinson R, Timans J, Shields J, Whittle N
Abstract excerpt
The CD44 cell surface glycoprotein is expressed on a broad range of different tissues as multiple isoforms containing from one to ten alternatively spliced exons v1-v10 inserted within the extracellular domain. Differential glycosylation generates still further variability, yielding both N- and O-glycan-modified forms of CD44 in addition to proteoglycan-like variants containing chondroitin sulphate and heparan...
Topics
- Alternative Splicing
- Base Sequence
- Carrier Proteins
- Cell Adhesion Molecules
- Cells, Cultured
- Chondroitin Sulfate Proteoglycans
- Cloning, Molecular
- Epithelial Cells
- Exons
- Extracellular Matrix Proteins