Article
The human type VI collagen gene. mRNA and protein variants of the alpha 3 chain generated by alternative splicing of an additional 5-end exon.
The Journal of biological chemistry - 25 Nov 1992
Zanussi S, Doliana R, Segat D, Bonaldo P, Colombatti A
Abstract excerpt
The amino- and carboxyl-terminal globular domains of type VI collagen are composed of several homologous modules similar to the type A collagen-binding modules present in von Willebrand factor. The human alpha 3(VI) chain that contributes most of the amino-terminal globule appears heterogeneous in size as a result of alternative splicing of two exons (Stokes D. G., Saitta, B., Timpl, R., and Chu, M.-L. (1991) J....
Topics
- Alternative Splicing
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Southern
- Chickens
- Collagen
- DNA, Neoplasm
- Exons
- Fluorescent Antibody Technique
- Genes