Article
The CD44 alternative v9 exon contains a splicing enhancer responsive to the SR proteins 9G8, ASF/SF2, and SRp20.
The Journal of biological chemistry - 29 Aug 2003
Galiana-Arnoux Delphine, Lejeune Fabrice, Gesnel Marie-Claude, Stevenin James, Breathnach Richard, Del Gatto-Konczak Fabienne
Abstract excerpt
The CD44 gene alternative exons v8, v9, and v10 are frequently spliced as a block by epithelial cells. By transfecting minigenes containing only one of these alternative exons, we show that splicing of each of them is under cell type-specific control. By using minigenes carrying short block mutations within exons v8 and v9, we detected a candidate exon splicing enhancer in each of these exons. These candidates...
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