Article
The other side of the nearly neutral theory, evidence of slightly advantageous back-mutations.
Proceedings of the National Academy of Sciences of the United States of America - 23 Oct 2007
Charlesworth Jane, Eyre-Walker Adam
Abstract excerpt
We argue that if there is a category of slightly deleterious mutations, then there should be a category of slightly advantageous back-mutations. We show that when there are both slightly deleterious and advantageous back-mutations, there is likely to be an increase in the rate of evolution after a population size expansion. This increase in the rate of evolution is short-lived. However, we show how its signature...
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