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Article

Loss and fixation of strongly favoured new variants: Understanding and extending Haldane's result via the Wright-Fisher model.

Bio Systems - 1 Nov 2022

Mavreas K, Gossmann T I, Waxman D

Abstract excerpt

The implications of Haldane's analysis for the fixation of beneficial alleles lies at the heart of much of 'population genetic thinking' and underlies many approaches that have been tailored to the detection of positive selection. Within the framework of a branching process, Haldane gave an approximation for the probability that fixation ultimately occurs when the selective advantage of a beneficial allele is...

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PMID: 35998748
DOI: 10.1016/j.biosystems.2022.104759

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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