Article
Moderating the neutralist-selectionist debate: exactly which propositions are we debating, and which arguments are valid?
Biological reviews of the Cambridge Philosophical Society - 1 Feb 2024
de Jong Menno J, van Oosterhout Cock, Hoelzel A Rus, Janke Axel
Abstract excerpt
Half a century after its foundation, the neutral theory of molecular evolution continues to attract controversy. The debate has been hampered by the coexistence of different interpretations of the core proposition of the neutral theory, the 'neutral mutation-random drift' hypothesis. In this review, we trace the origins of these ambiguities and suggest potential solutions. We highlight the difference between the...
Topics
- Selection, Genetic
- Biological Evolution
- Mutation
- Polymorphism, Genetic
- Evolution, Molecular