Article
[FLT3 internal tandem duplication in patients with acute promyelocytic leukemia].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Jun 2007
Zhu Yong-mei, Liu Yuan-fang, Zhang Su-jiang, Shen Zhi-xiang, Hu Jiong
Abstract excerpt
OBJECTIVE: To analyze the mutation of FLT3 internal tandem duplication (FLT3-ITD) in bone marrow cells from patients with newly-diagnosed acute promyelocytic leukemia (APL). METHODS: The mutation of FLT3-ITD in bone marrow mononuclear cells (MNCs) from 103 APL patients were screened by polymerase chain reaction (PCR) and the clinical features of ITD positive patients were analyzed. RESULTS: FLT3-ITD mutations...
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