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Article

ESCRTs and Fab1 regulate distinct steps of autophagy.

Current biology : CB - 23 Oct 2007

Rusten Tor Erik, Vaccari Thomas, Lindmo Karine, Rodahl Lina M W, Nezis Ioannis P, Sem-Jacobsen Catherine, Wendler Franz, Vincent Jean-Paul, Brech Andreas, Bilder David, Stenmark Harald

Abstract excerpt

Eukaryotes use autophagy to turn over organelles, protein aggregates, and cytoplasmic constituents. The impairment of autophagy causes developmental defects, starvation sensitivity, the accumulation of protein aggregates, neuronal degradation, and cell death [1, 2]. Double-membraned autophagosome...

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Identifiers

PMID: 17935992
DOI: 10.1016/j.cub.2007.09.032

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17935992-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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