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Article

Comparative proteome profiling and functional analysis of chronic myelogenous leukemia cell lines.

Journal of proteome research - 1 Nov 2007

Fontana Simona, Alessandro Riccardo, Barranca Marilisa, Giordano Margherita, Corrado Chiara, Zanella-Cleon Isabelle, Becchi Michel, Kohn Elise C, De Leo Giacomo

Abstract excerpt

The aim of the present study was the molecular profiling of different Ph+ chronic myelogenous leukemia (CML) cell lines (LAMA84, K562, and KCL22) by a proteomic approach. By employing two-dimensional gel electrophoresis combined with mass spectrometry analysis, we have identified 191 protein spots corresponding to 142 different proteins. Among these, 63% were cancer-related proteins and 74% were described for the...

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Share to Electrophoresis, Gel, Two-Dimensional
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Leukemic

Share to K562 Cells

Share to Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Share to Multivariate Analysis

Share to Neoplasm Invasiveness

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Source

Identifiers

PMID: 17935311
DOI: 10.1021/pr0704128

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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