Article
A quantitative analysis of heterogeneities and hallmarks in acute myelogenous leukaemia.
Nature biomedical engineering - 1 Nov 2019
Hu C W, Qiu Y, Ligeralde A, Raybon A Y, Yoo S Y, Coombes K R, Qutub A A, Kornblau S M
Abstract excerpt
Acute myelogenous leukaemia (AML) is associated with risk factors that are largely unknown and with a heterogeneous response to treatment. Here, we provide a comprehensive quantitative understanding of AML proteomic heterogeneities and hallmarks by using the AML Proteome Atlas, a proteomics database that we have newly derived from MetaGalaxy analyses, for the proteomic profiling of 205 patients with AML and 111...
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