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Genome-wide analysis of gene-expression profiles in chronic myeloid leukemia cells using a cDNA microarray

1 Sept 2003

Abstract excerpt

To characterize molecular mechanisms operating in chronic myeloid leukemia (CML) cells with a view toward development of novel therapeutic targets, we analyzed gene-expression profiles of cancer cells from 27 CML patients using a cDNA microarray representing 23,040 human genes. By comparing expression patterns of CML with those of normal cells, we identified 150 genes that were commonly highly up-regulated in CML...

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PMID: 12888904
DOI: 10.3892/ijo.23.3.681

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