Article
Proteomic cell surface phenotyping of differentiating acute myeloid leukemia cells.
Blood - 30 Sept 2010
Hofmann Andreas, Gerrits Bertran, Schmidt Alexander, Bock Thomas, Bausch-Fluck Damaris, Aebersold Rudolf, Wollscheid Bernd
Abstract excerpt
Immunophenotyping by flow cytometry or immunohistochemistry is a clinical standard procedure for diagnosis, classification, and monitoring of hematologic malignancies. Antibody-based cell surface phenotyping is commonly limited to cell surface proteins for which specific antibodies are available and the number of parallel measurements is limited. The resulting limited knowledge about cell surface protein markers...
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