Article
Targeted therapy in acute myeloid leukemia: current status and new insights from a proteomic perspective
2 Jan 2020
Abstract excerpt
Introduction: The biological heterogeneity of acute myeloid leukemia (AML) complicates personalized medicine. Individual prognosis is typically based on the presence of chromosomal and genetic lesions. Nevertheless, these classifications often lack a priori information about response to therapy. Since the protein expression landscape reflects the functional activity state of cells, we hypothesize that analyzing...
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