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Article

Direct selection of human genomic loci by microarray hybridization.

Nature methods - 1 Nov 2007

Albert Thomas J, Molla Michael N, Muzny Donna M, Nazareth Lynne, Wheeler David, Song Xingzhi, Richmond Todd A, Middle Chris M, Rodesch Matthew J, Packard Charles J, Weinstock George M, Gibbs Richard A

Abstract excerpt

We applied high-density microarrays to the enrichment of specific sequences from the human genome for high-throughput sequencing. After capture of 6,726 approximately 500-base 'exon' segments, and of 'locus-specific' regions ranging in size from 200 kb to 5 Mb, followed by sequencing on a 454 Life Sciences FLX sequencer, most sequence reads represented selection targets. These direct selection methods supersede...

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PMID: 17934467
DOI: 10.1038/nmeth1111

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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