Article
Microarray-based genomic selection for high-throughput resequencing.
Nature methods - 1 Nov 2007
Okou David T, Steinberg Karyn Meltz, Middle Christina, Cutler David J, Albert Thomas J, Zwick Michael E
Abstract excerpt
We developed a general method, microarray-based genomic selection (MGS), capable of selecting and enriching targeted sequences from complex eukaryotic genomes without the repeat blocking steps necessary for bacterial artificial chromosome (BAC)-based genomic selection. We demonstrate that large human genomic regions, on the order of hundreds of kilobases, can be enriched and resequenced with resequencing arrays....
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