Article
Hepatocyte nuclear factor 1 alpha is a factor responsible for the interindividual variation of OATP1B1 mRNA levels in adult Japanese livers.
Pharmaceutical research - 1 Dec 2007
Furihata Tomomi, Satoh Tomomi, Yamamoto Naoko, Kobayashi Kaoru, Chiba Kan
Abstract excerpt
PURPOSE: The aim of the present study was to clarify the factors responsible for interindividual variability of organic anion transporting polypeptide (OATP, gene symbol SLCO) 1B1 mRNA expression level in the human liver. MATERIALS AND METHODS: OATP1B1 mRNA expression levels were determined by real-time PCR in 31 human liver samples. The results were analyzed in relation to a single nucleotide polymorphism...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
