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Article

Hepatocyte nuclear factor-1 alpha is associated with UGT1A1, UGT1A9 and UGT2B7 mRNA expression in human liver.

The pharmacogenomics journal - 1 Apr 2008

Ramírez J, Mirkov S, Zhang W, Chen P, Das S, Liu W, Ratain M J, Innocenti F

Abstract excerpt

Experimental evidence suggests HNF1alpha regulates UGT expression. This study investigates (1) whether the variability in HNF1alpha expression is associated with the variability in UGT1A1, UGT1A9 and UGT2B7 expression in human livers and (2) the functionality of 12 HNF1alpha variants using mRNA e...

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Share to Gene Expression Regulation, Enzymologic
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Source

Identifiers

PMID: 17440429
DOI: 10.1038/sj.tpj.6500454

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17440429-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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