Polymorphisms in apoptosis- and proliferation-related genes, ionizing radiation exposure, and risk of breast cancer among U.S. Radiologic Technologists.

doi:10.1158/1055-9965.EPI-07-0282

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Article

Polymorphisms in apoptosis- and proliferation-related genes, ionizing radiation exposure, and risk of breast cancer among U.S. Radiologic Technologists.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Oct 2007

Sigurdson Alice J, Bhatti Parveen, Doody Michele M, Hauptmann Michael, Bowen Laura, Simon Steven L, Weinstock Robert M, Linet Martha S, Rosenstein Marvin, Stovall Marilyn, Alexander Bruce H, Preston Dale L, Struewing Jeffrey P, Rajaraman Preetha

Abstract excerpt

BACKGROUND: Although genes involved in apoptosis pathways and DNA repair pathways are both essential for maintaining genomic integrity, genetic variants in DNA repair have been thought to increase susceptibility to radiation carcinogenesis, but similar hypotheses have not generally been raised about apoptosis genes. For this reason, potential modification of the relationship between ionizing radiation exposure...

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Identifiers

PMID: 17932347
DOI: 10.1158/1055-9965.EPI-07-0282

Genes

CASP8

Variants

rs1045485

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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