Article
Novel breast cancer risk alleles and interaction with ionizing radiation among U.S. radiologic technologists.
Radiation research - 1 Feb 2010
Bhatti Parveen, Doody Michele M, Rajaraman Preetha, Alexander Bruce H, Yeager Meredith, Hutchinson Amy, Burdette Laurie, Thomas Gilles, Hunter David J, Simon Steven L, Weinstock Robert M, Rosenstein Marvin, Stovall Marilyn, Preston Dale L, Linet Martha S, Hoover Robert N, Chanock Stephen J, Sigurdson Alice J
Abstract excerpt
As genome-wide association studies of breast cancer are replicating findings and refinement studies are narrowing the signal location, additional efforts are necessary to elucidate the underlying functional relationships. One approach is to evaluate variation in risk by genotype based on known breast carcinogens, such as ionizing radiation. Given the public health concerns associated with recent increases in...
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