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Article

ATM haplotypes and cellular response to DNA damage: association with breast cancer risk and clinical radiosensitivity.

Cancer research - 15 Dec 2003

Angèle Sandra, Romestaing Pascale, Moullan Norman, Vuillaume Michèle, Chapot Brigitte, Friesen Marlin, Jongmans Wim, Cox David G, Pisani Paola, Gérard Jean-Pierre, Hall Janet

Abstract excerpt

The ATM gene, mutated in the cancer-prone and radiation-sensitive syndrome ataxia-telangiectasia (AT), could predispose to breast cancer (BC) development and adverse radiotherapy responses. Sixteen ATM variants were genotyped in 254 BC cases, 70 of whom were adverse radiotherapy responders (RS-BC), and 312 control subjects and the ATM haplotypes were constructed. Constitutive ATM protein, cell survival, and the...

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Source

Identifiers

PMID: 14695186

Genes

ATM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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ATM haplotypes and cellular response to DNA damage: association with breast cancer risk and clinical radiosensitivity.PMID 14695186Read ↗

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