Article
Nucleotide excision repair polymorphisms may modify ionizing radiation-related breast cancer risk in US radiologic technologists.
International journal of cancer - 1 Dec 2008
Rajaraman Preetha, Bhatti Parveen, Doody Michele Morin, Simon Steven L, Weinstock Robert M, Linet Martha S, Rosenstein Marvin, Stovall Marilyn, Alexander Bruce H, Preston Dale L, Sigurdson Alice J
Abstract excerpt
Exposure to ionizing radiation has been consistently associated with increased risk of female breast cancer. Although the majority of DNA damage caused by ionizing radiation is corrected by the base-excision repair pathway, certain types of multiple-base damage can only be repaired through the nucleotide excision repair pathway. In a nested case-control study of breast cancer in US radiologic technologists...
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