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Article

Polymorphisms in oxidative stress and inflammation pathway genes, low-dose ionizing radiation, and the risk of breast cancer among US radiologic technologists.

Cancer causes & control : CCC - 1 Nov 2010

Schonfeld Sara J, Bhatti Parveen, Brown Elizabeth E, Linet Martha S, Simon Steven L, Weinstock Robert M, Hutchinson Amy A, Stovall Marilyn, Preston Dale L, Alexander Bruce H, Doody Michele M, Sigurdson Alice J

Abstract excerpt

OBJECTIVE: Ionizing radiation, an established breast cancer risk factor, has been shown to induce oxidative damage and chronic inflammation. Polymorphic variation in oxidative stress and inflammatory-mediated pathway genes may modify radiation-related breast cancer risk. METHODS: We estimated breast cancer risk for 28 common variants in 16 candidate genes involved in these pathways among 859 breast cancer cases...

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Identifiers

PMID: 20711808
DOI: 10.1007/s10552-010-9613-7
PMCID: PMC3076104

Genes

PTGS2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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