Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Zinc Finger Antiviral Protein Acts Synergistically with an Interferon-Induced Factor for Maximal Activity against Alphaviruses

11 Oct 2007

Abstract excerpt

Type I interferons (IFNs) signal through specific receptors to mediate expression of genes, which together confer a cellular antiviral state. Overexpression of the zinc finger antiviral protein (ZAP) imparts a cellular antiviral state against Retroviridae, Togaviridae, and Filoviridae virus family members. Since ZAP expression is induced by IFN, we utilized Sindbis virus (SINV) to investigate the role of other...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Disease Management and Epidemiology
Share to Cytokine Signaling Pathways and Interactions
Share to interferon and immune responses

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17928353
DOI: 10.1128/jvi.00402-07

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Zinc Finger Antiviral Protein Acts Synergistically with an Interferon-Induced Factor for Maximal Activity against AlphavirusesPMID 17928353Read ↗

Multiple Interferon Stimulated Genes Synergize with the Zinc Finger Antiviral Protein to Mediate Anti-Alphavirus ActivitySemantic proximity Read ↗

Viral Induction of the Zinc Finger Antiviral Protein Is IRF3-dependent but NF-κB-independentSemantic proximity Read ↗

Expression of the Zinc-Finger Antiviral Protein Inhibits Alphavirus ReplicationSemantic proximity Read ↗

Endogenous ZAP is associated with altered Zika virus infection phenotype.Semantic proximity Read ↗

Zinc-Finger Antiviral Protein Inhibits XMRV InfectionSemantic proximity Read ↗

Inhibition of Hepatitis B Virus Replication by the Host Zinc Finger Antiviral ProteinSemantic proximity Read ↗

Targeted Restriction of Viral Gene Expression and Replication by the ZAP Antiviral SystemSemantic proximity Read ↗

Alphavirus Evasion of Zinc Finger Antiviral Protein (ZAP) Correlates with CpG Suppression in a Specific Viral nsP2 Gene SequenceSemantic proximity Read ↗

The Broad-Spectrum Antiviral Protein ZAP Restricts Human RetrotranspositionSemantic proximity Read ↗

The Role of ZAP and TRIM25 RNA Binding in Restricting Viral TranslationSemantic proximity Read ↗

Identification and Characterization of Interferon-Induced Proteins That Inhibit Alphavirus ReplicationSemantic proximity Read ↗

The Zinc Finger Antiviral Protein ZAP Restricts Human Cytomegalovirus and Selectively Binds and Destabilizes Viral UL4 / UL5 TranscriptsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.