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Article

The Broad-Spectrum Antiviral Protein ZAP Restricts Human Retrotransposition

22 May 2015

Abstract excerpt

Intrinsic immunity describes the set of recently discovered but poorly understood cellular mechanisms that specifically target viral pathogens. Their discovery derives in large part from intensive studies of HIV and SIV that revealed restriction factors acting at various stages of the retroviral life cycle. Recent studies indicate that some factors restrict both retroviruses and retrotransposons but surprisingly...

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Identifiers

PMID: 26001115
DOI: 10.1371/journal.pgen.1005252

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