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Article

Conformational motion of the ABC transporter MsbA induced by ATP hydrolysis.

PLoS biology - 1 Oct 2007

Borbat Peter P, Surendhran Kavitha, Bortolus Marco, Zou Ping, Freed Jack H, Mchaourab Hassane S

Abstract excerpt

We measured the amplitude of conformational motion in the ATP-binding cassette (ABC) transporter MsbA upon lipopolysaccharide (LPS) binding and following ATP turnover by pulse double electron-electron resonance and fluorescence homotransfer. The distance constraints from both methods reveal large-scale movement of opposite signs in the periplasmic and cytoplasmic part of the transporter upon ATP hydrolysis. LPS...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17927448
DOI: 10.1371/journal.pbio.0050271
PMCID: PMC2001213

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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