Article
Association of interleukin-1A, interleukin-1B and interleukin-1 receptor antagonist gene polymorphisms with multiple myeloma.
Leukemia & lymphoma - 1 Nov 2007
Abazis-Stamboulieh Danai, Oikonomou Pagona, Papadoulis Nikolaos, Panayiotidis Panayiotis, Vrakidou Efimia, Tsezou Aspasia
Abstract excerpt
Interleukin-1 (IL-1) is a cytokine involved in the maturation and proliferation of B cells and plays a significant role in the development of lytic bone lesions, a major clinical feature of multiple myeloma (MM) patients. Genes that regulate products involved in the immune system are highly polymorphic and contribute to inter-individual differences that can influence the genetic predisposition and progression of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
