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Article

Pharmacogenetic significance of inosine triphosphatase.

Pharmacogenomics - 1 Sept 2007

Bierau Jörgen, Lindhout Martijn, Bakker Jaap A

Abstract excerpt

Inosine triphosphatase (ITPase) is the enzyme that catalyzes the conversion of inosine triphosphate (ITP) and deoxy-inosine triphosphate (dITP) to inosine monophosphate and deoxy-inosine monophosphate, respectively, thereby maintaining low intracellular concentrations of ITP and dITP. Individuals deficient in ITPase activity were first recognized over 30 years ago. For decades, no clinical significance could be...

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PMID: 17924837
DOI: 10.2217/14622416.8.9.1221

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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