Article
Genome partitioning of genetic variation for height from 11,214 sibling pairs.
American journal of human genetics - 1 Nov 2007
Visscher Peter M, Macgregor Stuart, Benyamin Beben, Zhu Gu, Gordon Scott, Medland Sarah, Hill William G, Hottenga Jouke-Jan, Willemsen Gonneke, Boomsma Dorret I, Liu Yao-Zhong, Deng Hong-Wen, Montgomery Grant W, Martin Nicholas G
Abstract excerpt
Height has been used for more than a century as a model by which to understand quantitative genetic variation in humans. We report that the entire genome appears to contribute to its additive genetic variance. We used genotypes and phenotypes of 11,214 sibling pairs from three countries to partition additive genetic variance across the genome. Using genome scans to estimate the proportion of the genomes of each...
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