Article
Genome-wide association approaches for identifying loci for human height genes.
Best practice & research. Clinical endocrinology & metabolism - 1 Feb 2011
Perola Markus
Abstract excerpt
Human height is a very heritable trait as most of other human anthropometric traits. Genome-wide association studies have thus far identified about 200 genes associated with height with a genome-wide significance. Very large meta-analyses were needed to achieve this. These 200 height genes are involved in various biologically plausible pathways for growth, but yet explain only 10% of the variance in height. So it...
Topics
- Body Height
- Gene Frequency
- Genome, Human
- Genome-Wide Association Study
- Humans
- Meta-Analysis as Topic
- Polymorphism, Single Nucleotide
