Article

Analysis of 3.6 million individuals yields minimal evidence of pairwise genetic interactions for height

2024-08-17

Abstract excerpt

Adult height is a highly heritable polygenic trait with heritability attributable to thousands of independent variants. Large-scale studies have been able to detect genetic variants with contributions to height in the range of approximately 1.2 millimetre per allele copy on average. Non-additive genetic interactions may, in part, account for the difference between broad-sense and narrow-sense heritability estimate...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1fea45e3-1398-5858-aae9-89ccb151a431
DOI: 10.1101/2024.08.15.608197

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Analysis of 3.6 million individuals yields minimal evidence of pairwise genetic interactions for heightDOI 10.1101/2024.08.15.608197Read

A Saturated Map of Common Genetic Variants Associated with Human Height from 5.4 Million Individuals of Diverse AncestriesSemantic proximity Read

A saturated map of common genetic variants associated with human height.Semantic proximity Read

Common SNPs explain a large proportion of the heritability for human height.Semantic proximity Read

Genome partitioning of genetic variation for height from 11,214 sibling pairs.Semantic proximity Read

Meta-analysis of genome-wide association studies for height and body mass index in ∼700000 individuals of European ancestry.Semantic proximity Read

A commentary on 'common SNPs explain a large proportion of the heritability for human height' by Yang et al. (2010).Semantic proximity Read

Identification of ten loci associated with height highlights new biological pathways in human growth.Semantic proximity Read

Hundreds of variants clustered in genomic loci and biological pathways affect human height.Semantic proximity Read

Height matters-from monogenic disorders to normal variation.Semantic proximity Read

Defining the role of common variation in the genomic and biological architecture of adult human height.Semantic proximity Read

From Galton to GWAS: quantitative genetics of human height.Semantic proximity Read

Recent progress in the study of the genetics of height.Semantic proximity Read