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Article

ADD1 460W allele associated with cardiovascular disease in hypertensive individuals.

Hypertension (Dallas, Tex. : 1979) - 1 Jun 2002

Morrison Alanna C, Bray Molly S, Folsom Aaron R, Boerwinkle Eric

Abstract excerpt

High blood pressure is a predictor of cardiovascular disease. Hence, genes contributing to essential hypertension may play a role in the etiology of cardiovascular disease. For this reason, we examined the association between the alpha-adducin (ADD1) G460W and G-protein beta3 subunit (GNB3) 825C>T polymorphisms and the prevalence of peripheral arterial disease (PAD) and incidence of coronary heart disease (CHD)...

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Source

Identifiers

PMID: 12052841
DOI: 10.1161/01.hyp.0000019128.94483.3a

Genes

ADD1
GNB3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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